CRYPTOCOCCUS NEOFORMANS LATEX AGGLUTINATION SYSTEMS
The Latex-Cryto Antigen Detection System is a simple and rapid latex agglutination test for the qualitative and semi-quantitative detection of the capsular polysaccharide antigens of Cryptococcus neoformans in serum and cerbrospinal fluid (CSF). Cryptococcal antigen is frequently present in the serum of patients with pulmonary cryptococcosis and in the CSF and serum of patients with central nervous system involvement.
Currently, almost 50% of all cryptococcosis cases occur in HIV positive individuals. Other than AIDS patients, cryptococcosis occurs in normal individuals (rarely) and in subjects with impaired immune systems due to: 1) undelying diseases such as lupus erythematosis, sarcoidosis, leukemia, lymphoma and Cushman's Disease; 2) immuno suppressive therapies such as corticostreroids, cytotoxic drugs and transplantation therapies.
Since its introduction by IMMY in 1982, Detacher Enzyme (DE), Pronase®, has proven to be a vital component. DE digests antibodies in immune complexes (the antigen is not affected), which can mask the detection of antigens. DE also eliminates rheumatoid factor, which can cause false positives.
"Pronase" is a registered trademark of CALBIOCHEM Corporation.
Cryptococcus Latex Agglutination Systems
|CR1003||LATEX-CRYPTO ANTIGEN SYSTEM||Up to 50 Screening Tests|
|CR1004||LATEX-CRYPTO ANTIGEN SYSTEM||Up to 120 Screening Tests|
|CR1005||LATEX-CRYPTO ANTIGEN SYSTEM||Up to 240 Screening Tests|
Cryptococcus Latex Agglutination Reagents
|CB0010||Low-Cryptococcal Antigen Control||1 ml|
|CG0010||Anti-Cryptococcal Latex Reagent||3.5 ml|
|CG0020||Anti-Cryptococcal Latex Reagent||1.5 ml|
|DE0010||Detacher Enzyme||1.75 ml|
|EI0010||Enzyme Inhibitor (for DE)||6 ml|
|GB0020||Glycine Buffered Diluent with Albumin (GBDA, 10X Concentrate)||10 ml|
|N80010||Negative Control||1 ml|
|R20000||Anti-Globulin Control||2 ml|